Failure of an Extract of Pregnant Mares' Urine to Influence Gastric Secretion in Man

Abstract
The effect of Kutral (an extract of urine from pregnant mares) on the continuous basal gastric secretion was studied in 10 patients with active duodenal ulcer and 2 with gastric ulcer. The volume, free acidity, and output of HC1 were not significantly reduced despite the intro-gastric admn. of as much as 7.5 g. of the extract. No untoward effects were observed in these studies.