Congenital Malformations in Hamster Embryos after Treatment with Vinblastine and Vincristine
- 2 August 1963
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 141 (3579), 426
- https://doi.org/10.1126/science.141.3579.426
Abstract
Intravenous injection of vinblastine or vincristine, two antitumor chemotherapeutic agents used in humans, into pregnant golden hamsters on the 8th day of gestation, causes an increase in the fetal mortality rate and the appearance of a significant number of congenital malformations in the surviving fetuses.Keywords
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