Effect of Soybean Sterols on Liver Deposition of Cholesterol-G34

Abstract

Summary 1. The effect of soybean sterols A on liver deposition and fecal excretion of cholesterol-C₁₄ following a single feeding of I the labeled material has been studied using cholesterol-fed rats. Average recoveries of J labeled cholesterol in liver (measured as radioactivity recovered from liver non-saponifiable fraction) were 6.61% in a cholesterol-fed group, 1.80% in a cholesterol-fed group receiving one g of soy sterol immediately after cholesterol-C₁₄ administration and 0.47% in a group fed both cholesterol and soybean sterol for 120 days. 3. Average recoveries of radioactivity in the non-saponifiable fraction of feces were 20.14%, 25.13%, and 27.76%, respectively, for the 3 groups described above.