Collagen Has a Discrete Family of Reactive Hydroxylysyl and Lysyl Side-Chain Amino Groups
- 7 February 1969
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 163 (3867), 578-579
- https://doi.org/10.1126/science.163.3867.578
Abstract
Several cross-linking substances which derive from lysine have been isolated from hydrolyzates of collagen and elastin. This observation suggests that certain lysyl side chains exhibiting enhanced reactivity and unique configuration may participate in cross-linking. In native collagen there is a small family of lysyl and hydroxylysyl side chains which exhibit a high propensity of Schiff base formation.Keywords
This publication has 11 references indexed in Scilit:
- Intermediate labile intermolecular crosslinks in collagen fibresBiochimica et Biophysica Acta (BBA) - Protein Structure, 1968
- Intermolecular Cross-links in Reconstituted Collagen FibrilsPublished by Elsevier ,1968
- Isolation and Partial Characterization of a New Amino Acid from Reduced Elastin*Biochemistry, 1967
- The derangement of elastin synthesis in pyridoxine deficiencyBiochemical and Biophysical Research Communications, 1967
- Molecular Diseases of Connective and Vascular Tissues. II. Amine Oxidase Inhibition by the Lathyrogen, β-Aminopropionitrile*Biochemistry, 1967
- The Nature of the Intramolecular Cross-Links in Collagen. The Separation and Characterization of Peptides from the Cross-Link Region of Rat Skin Collagen*Biochemistry, 1966
- Identification of a new crosslinking amino acid in elastinBiochemical and Biophysical Research Communications, 1965
- Degradation Products from Elastin: Partial Structure of Two Major Degradation Products from the Cross-linkages in ElastinNature, 1963
- Transfer of Amino Acids across the Intestine: a New Model Amino AcidJournal of Biological Chemistry, 1962
- Heritable disorders of connective tissue: VIII. Concluding commentsJournal of Chronic Diseases, 1956