Bilirubin and alkaline phosphatase clearance from blood-plasma by perfusion through activated carbon

Abstract

A prepared solution, human urine, bile, and stored blood were perfused through a carbon column. Urea, bilirubin, and calcium were adsorbed in particular, and the fluids became progressively more alkaline. Ammonia was not absorbed. In 6 dogs with obstructive jaundice, a haemoperfusion through a similar carbon column was carried out. A simple technique avoiding serious damage to the blood-cell elements is described. A reduction of the serum bilirubin and of the serum alkaline phosphatase occurred after haemoperfusion.