An Electrophoretic and Quantitative Analysis of Coagulation Factor XIII in Normal and Deficient Subjects
- 1 August 1980
- journal article
- research article
- Published by Wiley in British Journal of Haematology
- Vol. 45 (4), 633-640
- https://doi.org/10.1111/j.1365-2141.1980.tb07186.x
Abstract
Previous electrophoretic studies of the A and B subunits of factor XIII have revealed considerable genetic heterogeneity. The electrophoretic forms were investigated and the A and B subunits were quantitated in a family with inherited factor XIII deficiency. The deficiency in this family was apparently due to a null allele at the locus controlling the A subunit. All family members had decreased levels of B subunit. There was no difference in thrombin activated transamidase activity between normal individuals with the 3 commonly occurring electrophoretic phenotypes of the A subunit.This publication has 18 references indexed in Scilit:
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