Epidemiological Aspects of Neonatal Necrotizing Enterocolitis
- 1 August 1974
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Pediatrics & Adolescent Medicine
- Vol. 128 (2), 186-190
- https://doi.org/10.1001/archpedi.1974.02110270060012
Abstract
Detailed attempts to isolate pathogens were made during an apparent epidemic outbreak of neonatal necrotizing enterocolitis (NEC). In addition, all cases of infants with this disease since 1964 were reviewed for comparison with the present outbreak. Efforts were made to determine a transmissible cause. No bacteria, virus, or fungus common to the infants involved in the outbreak was isolated. Neither could any other transmissible cause be implicated. It appears that the organisms involved in NEC are normal bowel flora that enter the peritoneum and blood stream through an altered gut mucosa.Keywords
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