A SATELLITED HUMAN Y CHROMOSOME: AN EVIDENCE OF AUTOSOME GONOSOME TRANSLOCATION A PRELIMINARY NOTE
- 1 September 1967
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Genetics and Cytology
- Vol. 9 (3), 589-595
- https://doi.org/10.1139/g67-063
Abstract
A Y chromosome with satellites on the long arms was found in 100 analysed metaphases of short-term cultured blood leukocytes from a 25-year-old trisomy-21 Mongoloid male. Satellite association was found in 68 of the cells; the mean number of associations was 0.94 per cell. The association frequency for individual chromosomes was 19.5% for group D autosomes, 13.8% for group G autosomes and 21.0% for the Y gonosome. An identical Y was present in leukocyte cultures of the father, a brother, a paternal uncle and nephew, all normal individuals. A translocation between a satellited acrocentric autosome and the Y chromosome following spontaneous breakage in the meiotic cells of an untested male ancestor is postulated.This publication has 18 references indexed in Scilit:
- Presumptive Y/D translocation in mixed gonadal dysgenesis.Journal of Medical Genetics, 1967
- Association of human satellited chromosomesCellular and Molecular Life Sciences, 1966
- Size variation and orientation of the human Y chromosomeChromosoma, 1964
- Cytogenetic studies in leucocytes on the general population: subjects of ages 65 years and moreAnnals of Human Genetics, 1963
- PRODUCTION OF A SEMI-PURIFIED PHYTOHÆMAGGLUTININ (MUCOPROTEIN) OF HIGH POTENCY FOR THE STUDY OF CHROMOSOMES OF LEUCOCYTESThe Lancet, 1963
- Chromosome Studies in Mongoloids and Their FamiliesCytogenetic and Genome Research, 1963
- An aberrant small acrocentric chromosomeAnnals of Human Genetics, 1962
- Polyploidy with Chromosome Breakage at Meiosis in the Human MaleCytogenetic and Genome Research, 1962
- OBSERVATIONS ON THE SATELLITED HUMAN CHROMOSOMESThe Lancet, 1961
- Amino Acid Metabolism in Mammalian Cell CulturesScience, 1959