Auxological data and final height were analysed in 42 patients with growth hormone deficiency (GHD), 10 had isolated GHD (group 1), 23 had multiple pituitary hormone deficiencies (group 2) and 9 had organic GHD (group 3). Patients received growth hormone (GH) for a mean of 6.5 ± 2.6 (group 1), 8.0 ± 2.9 (group 2) and 2.9 ± 1.5 years (group 3). Most patients were treated with pituitary GH (pGH), 11 IU/m2/week (mean) in 3 divided doses, which was not changed during puberty. Six patients, treated with daily injections of recombinant GH, showed a significantly better height velocity than those treated with pGH (2.1 vs. -0.3 SDS), though the mean dose was identical (p = 0.03). Final heights for boys and girls were -2.8 and -3.3 SDS (group 1), -1.9 and -1.6 SDS (group 2), and -2.9 and -3.2 SDS (group 3). Only 20% of group 1 70% of group 2 and 22% of group 3 reached final heights within target limits. Final height was positively correlated with height at onset of puberty, but there was no association with the timing or magnitude of pubertal growth.