Proteinpolysaccharide in Connective Tissue: Inhibition of Phase Separation
- 22 November 1963
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 142 (3595), 1073-1075
- https://doi.org/10.1126/science.142.3595.1073
Abstract
A macromolecule of protein and chondroitin sulfate (PP-L) inhibits sedimentation of barium-polystyrene sulfonate (BaPSS) and of calcium phosphate at low but not at high values of gravity. Sedimentation of BaPSS removes a large fraction of PP-L from solution, but sedimentation of calcium phosphate does not. The results suggest entanglement among linear polyanionic chains.Keywords
This publication has 11 references indexed in Scilit:
- The effect of hyaluronic acid on the sedimentation rate of other substancesBiochimica et Biophysica Acta, 1961
- ULTRACENTRIFUGAL SEPARATION OF THE METACHROMATIC COMPOUND OF METHYLENE BLUE AND CHONDROITIN SULFATE1The Journal of Physical Chemistry, 1961
- The partition of solutes between buffer solutions and solutions containing hyaluronic acidBiochemical Journal, 1961
- A structural function of mucopolysaccharide in connective tissueBiochemical Journal, 1960
- Sodium chondroitin sulfate-protein complexes of cartilage. I. Molecular weight and shapeArchives of Biochemistry and Biophysics, 1958
- The Binding of Cations by Chondroitin SulfateJCI Insight, 1957
- A Simple Spectrophotometry Method for the Determination of CalciumAmerican Journal of Clinical Pathology, 1957
- THE COLORIMETRIC DETERMINATION OF PHOSPHORUSJournal of Biological Chemistry, 1925