S-adenosylmenthionine decarboxylase as an enzyme target for therapy
- 31 December 1992
- journal article
- review article
- Published by Elsevier in Pharmacology & Therapeutics
- Vol. 56 (3), 359-377
- https://doi.org/10.1016/0163-7258(92)90025-u
Abstract
No abstract availableKeywords
This publication has 52 references indexed in Scilit:
- Cure of murine Trypanosoma brucei rhodesiense infections with an S-adenosylmethionine decarboxylase inhibitorAntimicrobial Agents and Chemotherapy, 1992
- Cytostasis induced in L1210 murine leukaemia cells by the S-adenosyl-l-methionine decarboxylase inhibitor 5′-([(Z)-4-amino-2-butenyl]methylamino)-5′-deoxyadenosine may be due to hypusine depletionBiochemical Journal, 1992
- Uptake of the antitrypanosomal drug 5′-{[(Z)-4-amino-2-butenyl]methylamino}-5′-deoxyadenosine (MDL 73811) by the purine transport system of Trypanosoma brucei bruceiBiochemical Journal, 1992
- Alkylation of an active-site cysteinyl residue during substrate-dependent inactivation of Escherichia coli S-adenosylmethionine decarboxylaseBiochemistry, 1991
- Regulation of S‐adenosylmethionine decarboxylase in L1210 leukemia cellsEuropean Journal of Biochemistry, 1991
- Antitrypanosomal effects of polyamine biosynthesis inhibitors correlate with increases in Trypanosoma brucei brucei S-adenosyl-l-methionineBiochemical Journal, 1991
- Irreversible inhibition of rat S-adenosylmethionine decarboxylase by 5′-{[(Z)-4-amino-2-butenyl]methylamino}-5′-deoxyadenosineBiochemical Pharmacology, 1990
- Cure of Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense infections in mice with an irreversible inhibitor of S-adenosylmethionine decarboxylaseAntimicrobial Agents and Chemotherapy, 1990
- 5'-{[(Z)-4-Amino-2-butenyl]methylamino}-5'-deoxyadenosine: a potent enzyme-activated irreversible inhibitor of S-adenosyl-L-methionine decarboxylase from Escherichia coliJournal of the American Chemical Society, 1989
- Mechanism of substrate inactivation of Escherichia coli S-adenosylmethionine decarboxylaseBiochemistry, 1987