Novel Plasmid-Encoded Class C β-Lactamase (MOX-2) in Klebsiella pneumoniae from Greece
- 1 July 2002
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 46 (7), 2262-5
- https://doi.org/10.1128/aac.46.7.2262-2265.2002
Abstract
Klebsiella pneumoniae KOL, a clinical strain resistant to various β-lactams, was isolated from the stools of a patient from Greece. This strain harbored a new pI 9.1 plasmid-mediated AmpC β-lactamase with unusually high levels of hydrolytic activity for cefoxitin and cefotetan that we named MOX-2. Sequencing of bla MOX-2 revealed 93.2, 92.9, 92.7, and 73.1% identities with the deduced amino acid sequences of CMY-8, MOX-1, CMY-1, and the AmpC β-lactamase of Aeromonas sobria , respectively.Keywords
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