Mechanisms of Wound Healing

Abstract

THE presence of a factor promoting the rehealing of wounds has been postulated for many years. The excellent healing of the resutured dehiscence has often been noted clinically.¹ However, evidence of the nature of the factor or factors responsible for this effect has been lacking.A systemic healing-promoting factor was proposed by Sandblom² as being responsible for the increased rate of healing that he found in wounds made after a given time at a distance from a primary wound. The greatest effect seemed to be present during the second week after wounding. This concept has been disputed by Taffel, Donovan . . .