Effects of Sudden Aortic Occlusion on Heart Rate After Sino-Aortic Denervation

Abstract

This study tests the possibility that pressoreceptors of the sinoaortic type may be located in thoracic vessels and innervated by thoracic afferent nerves. Heart rate and arterial pressure were recorded in anesthetized dogs with neural pathways intact, bilateral vagotomy and sinoaortic denervation before and after internal occlusion of the aorta just above the celiac artery. Results obtained indicate that after elimination of the sinoaortic mechanisms by vagotomy and isolation of the carotid sinuses no functional pressoreceptors of the sinoaortic type can be demonstrated in the arterial tree above the celiac artery.