The delivery of an aqueous aerosol containing non-volatile odorants to the olfactory epithelium of the rat

Abstract

We describe an apparatus which can deliver a pulse of aerosol to a preparation of olfactory tissue. Non-volatile compounds in the aerosol produce an increase in the electro-olfactogram response of the rat. The concentration of the non-volatile compounds at which a response is seen is – 1800 times higher than that of the volatile odorant i-pentyl acetate, which is used as the reference stimulus.