High Frequency of Mutator Strains among Human Uropathogenic Escherichia coli Isolates
Open Access
- 15 January 2002
- journal article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 184 (2), 605-9
- https://doi.org/10.1128/jb.184.2.605-609.2002
Abstract
By using a panel of 603 commensal and pathogenic Escherichia coli and Shigella isolates, we showed that mutation rates of strains vary considerably among different ecotypes. Uropathogenic strains had the highest frequency of mutators, while strains from patients with bacteremia had the lowest mutation rates. No correlation between the mutation rates and antibiotic resistance was observed among the studied strains.Keywords
This publication has 29 references indexed in Scilit:
- Costs and Benefits of High Mutation Rates: Adaptive Evolution of Bacteria in the Mouse GutScience, 2001
- Biofilm Formation in a Hydrodynamic Environment by Novel FimH Variants and Ramifications for VirulenceInfection and Immunity, 2001
- Mutator Natural Escherichia coli Isolates Have an Unusual Virulence PhenotypeInfection and Immunity, 2001
- Prevalence of Virulence Genes and Clonality in Escherichia coli Strains That Cause Bacteremia in Cancer PatientsInfection and Immunity, 2000
- High Frequency of Hypermutable Pseudomonas aeruginosa in Cystic Fibrosis Lung InfectionScience, 2000
- Effects of Environment on Compensatory Mutations to Ameliorate Costs of Antibiotic ResistanceScience, 2000
- Shigella and enteroinvasive Escherichia coli strains are derived from distinct ancestral strains of E. coliMicrobiology, 1998
- Highly Variable Mutation Rates in Commensal and Pathogenic Escherichia coliScience, 1997
- High Mutation Frequencies Among Escherichia coli and Salmonella PathogensScience, 1996
- Potential of Escherichia coli isolated from nature to propagate cloning vectorsNature, 1980