QUANTITATIVE RESPONSE OF THE RAT OVARY TO PITUITARY GONADOTROPIN AS MODIFIED BY ESTROGEN1
- 1 September 1959
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 65 (3), 383-388
- https://doi.org/10.1210/endo-65-3-383
Abstract
A purified pituitary gonadotropin predominantly FSH activity was administered in graded doses to hypophysectomized and intact immature female rats, with and without concurrent administration of diethylstilbestrol in large doses. A more striking and consistent ovarian weight increase to pituitary gonadotropin, brought about 4111-4117 ENDOCRINE SYSTEM [Vol. 35] 356 through stimulation of early ovarian follicle development, regulation of further follicular progression, and depression of interstitial tissue overgrowth was observed in the diethylstilbestrol-treated hypophysecto-mized animals.Keywords
This publication has 5 references indexed in Scilit:
- ASSAY OF FOLLICLE-STIMULATING HORMONE IN THE HYPOPHYSECTOMIZED ESTROGEN-TREATED IMMATURE FEMALE RAT1Endocrinology, 1959
- THE INFLUENCE OF ESTROGEN AND ANDROGEN ON THE OVARIAN RESPONSE OF HYPOPHYSECTOMIZED IMMATURE RATS TO GONADOTROPINS1Endocrinology, 1958
- SYNERGISM BETWEEN PITUITARY FOLLICLE STIMULATING HORMONE (FSH) AND HUMAN CHORIONIC GONADOTROPIN (HCG)1Endocrinology, 1951
- STUDIES ON THE ASSAY OF PITUITARY GONADOTROPINS USING THE AUGMENTATION REACTIONEndocrinology, 1942
- THE BULLETIN OFTHE BULLETIN OF THE ASSOCIATION FOR THE STUDY OF INTERNAL SECRETIONSEndocrinology, 1939