Lower respiratory infection and inflammation in infants with newly diagnosed cystic fibrosis
- 17 June 1995
- Vol. 310 (6994), 1571-1572
- https://doi.org/10.1136/bmj.310.6994.1571
Abstract
The state of Victoria, Australia (66000 births per year) has a cystic fibrosis screening programme, all patients being managed by one centre. Between February 1992 and September 1994 we recruited 45 (27 boys) of the 52 infants with newly diagnosed disease; 32 were identified by screening, 12 from meconium ileus, and one by failure to thrive, and all cases were confirmed by sweat testing. Sixteen infants had respiratory symptoms, and seven of them were receiving oral antibiotics when bronchoalveolar lavage was performed at a mean age of 2.6 (SD 1.6) months. Nine otherwise healthy infants (five boys) aged 2-33 (median 8) months who were undergoing bronchoscopy for stridor served as controls.Keywords
This publication has 5 references indexed in Scilit:
- Bronchoalveolar lavage findings in cystic fibrosis patients with stable, clinically mild lung disease suggest ongoing infection and inflammation.American Journal of Respiratory and Critical Care Medicine, 1994
- Protease-antiprotease imbalance in the lungs of children with cystic fibrosis.American Journal of Respiratory and Critical Care Medicine, 1994
- Early bacteriologic, immunologic, and clinical courses of young infants with cystic fibrosis identified by neonatal screeningThe Journal of Pediatrics, 1991
- Predictive Value of Oropharyngeal Cultures for Identifying Lower Airway Bacteria in Cystic Fibrosis PatientsAmerican Review of Respiratory Disease, 1991
- Diagnosing Bacterial Respiratory Infection by Bronchoalveolar LavageThe Journal of Infectious Diseases, 1987