Effect of premedication on the induction dose of thiopentone in children
- 1 May 1984
- journal article
- clinical trial
- Published by Wiley in Anaesthesia
- Vol. 39 (5), 426-428
- https://doi.org/10.1111/j.1365-2044.1984.tb07309.x
Abstract
The effective dose of thiopentone in 90% ( ED90 ) of unpremedicated children is 10.5 mg/kg. This is significantly greater (p less than 0.01) than in premedicated children. The ED90 in children premedicated with TDP (a mixture of trimeprazine , droperidol and physeptone with atropine) is 4.2 mg/kg which is significantly less (p less than 0.05) than with trimeprazine and atropine ( ED90 5.2 mg/kg) or papaveretum and hyoscine ( ED90 5.0 mg/kg).Keywords
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