La S-adénosyl-L-homocystéine : 2. Anticonvulsivante
- 1 May 1980
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Physiology and Pharmacology
- Vol. 58 (5), 493-498
- https://doi.org/10.1139/y80-082
Abstract
S-Adenosyl-L-homocysteine (SAH) decreases the epileptiform discharges induced by hippocampic stimulation in rats. SAH reduces pentetrazol convulsions, does not modify picrotoxin convulsions and increases strychnine toxicity. These effects are not linked to GABA metabolism perturbation or to the concentration of some amino acids known for their action in synaptic transmission.This publication has 4 references indexed in Scilit:
- The Prolonged Anticonvulsant Action of Taurine on Genetically Determined Seizure-SusceptibilityCanadian Journal of Neurological Sciences, 1978
- Influence of taurine dosage on cobalt epilepsy in miceNeurochemical Research, 1978
- ISOLATION AND IDENTIFICATION OF γ‐AMINOBUTYRYL‐CYSTATHIONINE FROM HUMAN BRAIN AND CSFJournal of Neurochemistry, 1977
- S-Adenosyl-l-homocysteine in brainNeurochemical Research, 1977