CELLULAR SOURCE AND CHARACTER OF A HEAT-STABLE BACTERICIDAL PROPERTY ASSOCIATED WITH RABBIT AND RAT PLATELETS
Open Access
- 1 April 1961
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 113 (4), 701-711
- https://doi.org/10.1084/jem.113.4.701
Abstract
Rabbit and rat platelets contain two non-dialyzable components (analogous to Myrvik's components 1 and 2 of serum) which, together with bicarbonate ions, produce a potent bactericidin for B. subtilis. These platelet factors appear to be identical with the serum bactericidal substances, suggesting that disruption of platelets during blood coagulation releases the platelet factors into serum. Normal human platelets contain no measurable component 1 or 2.Keywords
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