A Comparative Evaluation of Whey Hydrolysate and Whey-Predominant Formulas
- 2 July 1993
- journal article
- clinical trial
- Published by SAGE Publications in Clinical Pediatrics
- Vol. 32 (7), 433-437
- https://doi.org/10.1177/000992289303200708
Abstract
Whey hydrolysate formulas are a recent and important innovation in infant feeding. This study compared clinical tolerance and acceptability of a whey hydrolysate formula (WH) with those of a whey-predominant formula (WF) in 45 infants. Four infants (16%) who refused to drink WH formula were eliminated from the study. Mean volume intake was significantly lower for WH (120 mL/kg/day) than for WF (147 mL/kg/day; P <.001). Consequently, mean caloric intake was also significantly different: 80 kcal/kg/day (WF) vs 97 kcal/kg/day (WF; P <.001). Nevertheless, weight gain from birth to 13 weeks of age was nearly identical in both groups (171% for WH vs 178% for WF). No significant differences were noted in duration of feeding, number of pauses during feeding, number of stools per day, or number of regurgitations per day. The lower rate of caloric intake and the dropout rate of 16% for WH raise questions about the use of WH formula in normal infants, as has become the case in some Western European regions.Keywords
This publication has 5 references indexed in Scilit:
- Positive and negative titres of a new serologic test for the detection of Helicobacter pyloriEuropean Journal of Gastroenterology & Hepatology, 1993
- Gastric Emptying Using Three Different Formulas in Infants with Gastroesophageal RefluxJournal of Pediatric Gastroenterology and Nutrition, 1992
- Effect of allergen avoidance on development of allergic disorders in infancyThe Lancet, 1992
- Decrease in gastric emptying time and episodes of regurgitation in children with spastic quadriplegia fed a whey-based formulaThe Journal of Pediatrics, 1992
- An Evaluation With Piglets of Bovine Milk, Hydrolyzed Bovine Milk, and Isolated Soybean Proteins Included in Infant Milk Formulas. II. Stomach-Emptying Rate and the Postprandial Change in Gastric pH and Milk-Clotting Enzyme ActivityJournal of Pediatric Gastroenterology and Nutrition, 1991