Ten-year incidence and risk factors of bone fractures in a cohort of treated HIV1-infected adults
- 15 May 2009
- journal article
- research article
- Published by Wolters Kluwer Health in AIDS
- Vol. 23 (8), 1021-1024
- https://doi.org/10.1097/qad.0b013e3283292195
Abstract
In the ANRS CO8 APROCO-COPILOTE cohort of patients treated with combination antiretroviral therapy since 1997–1999, the incidence density of bone fractures was 3.3 for 1000 patient-years [95% confidence interval (CI) = 2.0–4.6]. The rate was 2.9-fold (95% CI = 1.3–6.5) higher among patients with excessive alcohol consumption and 3.6-fold (95% CI = 1.6–8.1) higher in those with hepatitis C virus (HCV) coinfection. Specific monitoring of HCV/HIV-coinfected patients and active promotion of alcohol cessation should be recommended for the prevention of bone fractures.Keywords
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