A DOUBLE‐BLIND STUDY OF THE INFLUENCE OF TRANEXAMIC ACID ON THE CENTRAL CORNEAL THICKNESS AFTER CATARACT EXTRACTION
- 1 February 1978
- journal article
- research article
- Published by Wiley in Acta Ophthalmologica
- Vol. 56 (1), 121-126
- https://doi.org/10.1111/j.1755-3768.1978.tb00474.x
Abstract
A double-blind study of the influence of systemic tranexamic acid on the central corneal thickness after cataract extraction was performed in 17 pairs of patients. Sequential statistics showed that the increase in central corneal thickness after surgery was significantly less in the tranexamic acid treated group than in the placebo group. There was no significant difference in intraocular pressure between the tranexamic acid and the placebo treated group. The possible influence of tranexamic acid on the thickness controlling mechanism of the cornea is discussed, and studies concerning the fibrinolytic system, the complement system and the aqueous humor amino acid treated patients are mentioned.Keywords
This publication has 8 references indexed in Scilit:
- BULLOUS KERATOPATHY (FUCHS‘ ENDOTHELIAL DYSTROPHY) TREATED SYSTEMICALLY WITH 4-TRANS-AMINO-CYCLOHEXANO-CARBOXYLIC ACIDActa Ophthalmologica, 2009
- PROGRESS IN CATARACT SURGERY USING MICROSURGICAL TECHNIQUEActa Ophthalmologica, 1978
- A TECHNICAL IMPROVEMENT OF THE HAAG‐STREIT PACHOMETER Short CommunicationActa Ophthalmologica, 1977
- Studies on renal tubular protein reabsorption: Partial and near complete inhibition by certain amino acidsScandinavian Journal of Clinical and Laboratory Investigation, 1977
- Cataract Extraction and the Corneal EndotheliumAmerican Journal of Ophthalmology, 1976
- CORNEAL THICKNESS AFTER CATARACT EXTRACTION WITH AIR IN THE ANTERIOR CHAMBERActa Ophthalmologica, 1975
- Inhibition by ɛ-Aminocaproic Acid of the Activation of the First Component of the Complement SystemThe Journal of Immunology, 1975