Cutaneous changes in diseases of disturbed metabolism are occupying more and more attention of dermatologists. In 19331 we described a case of systematized amyloidosis and reviewed the reports of cases in which cutaneous involvement was a prominent feature. Since then we have examined a patient presented by Dr. Paul O'Leary2 before the summer meeting of the Minnesota Dermatological Society held at Rochester, Minn., on July 28, 1934, and more recently we were so fortunate as to have still another such case in our own wards. The literature on localized amyloidosis has been enriched in the past year by the reports of Nomland and Plummer,3 Urbach,4 Walther,5 Gray,6 Scolari,7 Sannicandro8 and Matras.9 It is worthy of mention that amyloid is found with a certain regularity in chronic conditions of the skin the morphologic changes of which do not suggest the presence