Development of myasthenia gravis in two patients with multiple sclerosis following interferon treatment

Abstract

A 41 year old right-handed woman was diagnosed 3 years ago with relapsing-remitting multiple sclerosis (MS) with positive MRI findings and positive CSF for oligoclonal bands. Her neurological symptoms were long-standing, starting at the age of 20. Her family history was positive for MS, her father being a sufferer. Her past medical history was unremarkable. Since March 2001 she has been receiving interferon 1β and symptomatic treatment for neurogenic pain and occasional tonic muscle spasms.