Detection of human papillomavirus-6 in primary carcinoma of the urethra in men
- 15 October 1987
- Vol. 60 (8), 1832-1835
- https://doi.org/10.1002/1097-0142(19871015)60:8<1832::aid-cncr2820600826>3.0.co;2-2
Abstract
The authors report a case of primary urethral carcinoma which seems to be linked to human papillomavirus (HPV) infection. Southern blot hybridization of phosphorus 32 (32P)-labeled DNA extracted from the cancer tissue gave a positive reaction with HPV-6. Specimens of the tumor material subjected to in situ hybridization with 3H-labeled HPV-6 DNA showed numerous tumor cell clusters with clearly labeled nuclei. Using immunoperoxidase staining the authors found papillomavirus structural antigen within cell nuclei of the tumor tissue.This publication has 23 references indexed in Scilit:
- Primary Penile Urethral CarcinomaBritish Journal of Urology, 1986
- Carcinoma of the Male UrethraJournal of Urology, 1985
- Carcinoma in diverticulum of female urethraUrology, 1985
- Papillomavirus Structural Antigens in Condyloma Acuminatum of the Male UrethraJournal of Urology, 1983
- Partial characterization of viral DNA from human genital warts (condylomata acuminata)International Journal of Cancer, 1980
- Urethral CancerCancer, 1980
- Pathology and natural history of urethral tumors in males Review of 142 casesUrology, 1978
- Tumors of the urethra in men and womenCancer, 1973
- Carcinoma of the Male UrethraJournal of Urology, 1967
- Primary Carcinoma of the Male UrethraJournal of Urology, 1966