Gamma Hydroxybutyrate and Gamma Butyrolactone: Concentration in Rat Tissues during Anesthesia
- 6 March 1964
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 143 (3610), 1045-1047
- https://doi.org/10.1126/science.143.3610.1045
Abstract
Gamma-hydroxybutyric acid, when administered to animals or human beings, causes sleep. It is convertible to gamma-butyrolactone, which also produces sleep. Tissue concentrations in rats after administration of these two compounds show that the induced sleep is related to the concentration of the lactone in the brain.Keywords
This publication has 3 references indexed in Scilit:
- γ-Hydroxybutyrate in Mammalian BrainPublished by Elsevier ,1964
- THE THERAPY OF EXPERIMENTAL INFLUENZA IN MICE WITH ANTIBIOTIC LACTONES AND RELATED COMPOUNDS1947
- A PHOTOMETRIC ADAPTATION OF THE SOMOGYI METHOD FOR THE DETERMINATION OF GLUCOSEJournal of Biological Chemistry, 1944