A CONTROLLED TRIAL OF EXTRADURAL FENTANYL IN LABOUR
- 1 April 1982
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 54 (4), 409-414
- https://doi.org/10.1093/bja/54.4.409
Abstract
In a double-blind trial carried out on patients in the 1st stage of labor, either fentanyl 80 .mu.g (no. = 35) or physiological saline (no. = 33) was added to the test dose of bupivacaine and administered extradurally. Thereafter, analgesia was maintained as necessary with 0.5% bupivacaine alone. Supplementary bupivacaine (a further dose within 1 h) was required to produce satisfactory analgesia in 8 patients in the fentanyl group and in 26 patients in the control group. Analgesia was more rapid in onset and more complete in the fentanyl group, and the duration from 1st dose to 1st top-up was 2.36 h, compared with 1.66 h (supplements notwithstanding) in the control group. No serious side-effects were encountered in either group, although 8 patients in the fentanyl group experienced mild itching, compared with 1 in the control group.This publication has 8 references indexed in Scilit:
- Double-blind Comparison of Morphine and Bupivacaine for Continuous Epidural Analgesia in LaborAnesthesiology, 1981
- Serum Levels Following Epidural Administration of Morphine and Correlation with Relief of Postsurgical PainAnesthesiology, 1981
- Intrathecal Injection of Morphine for Obstetric AnalgesiaAnesthesiology, 1981
- Pain Control with Epidural Injection of MorphineAnesthesiology, 1980
- EXPERIMENTAL COMPARISON OF EXTRADUPAL AND I.M. MORPHINEBritish Journal of Anaesthesia, 1980
- Epidural Narcotics for Postoperative AnalgesiaAnesthesia & Analgesia, 1980
- OBSERVATIONS ON EXTRADURAL MORPHINE ANALGESIA IN VARIOUS PAIN CONDITIONSBritish Journal of Anaesthesia, 1980
- Analgesia Mediated by a Direct Spinal Action of NarcoticsScience, 1976