Chinese Herbs and Urothelial Carcinoma

Abstract

The patients described by Nortier et al. (June 8 issue)¹ took not only a Chinese herb but also dexfenfluramine, acetazolamide, amphetamines, theophylline, and deadly nightshade.^2,3 The confounding factor of drug interactions was not discussed in the article. More important, the smoking habits of these patients were not detailed, and the investigators did not look for the DNA adducts associated with dexfenfluramine and cigarette tar.