Symmetry mismatch and DNA packaging in large bacteriophages.
- 1 October 1978
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 75 (10), 4779-4783
- https://doi.org/10.1073/pnas.75.10.4779
Abstract
A model is presented for the mechanism of packaging double-stranded DNA into phage heads. The model is based on, and rationalizes, the mismatch in symmetry between the heads and tails of large bacteriophages. DNA movement is postulated to be mediated by a rotating protein structure at the tail-proximal vertex of the head.This publication has 44 references indexed in Scilit:
- Studies on the structure, protein composition and assembly of the neck of bacteriophage T4Journal of Molecular Biology, 1977
- DNA packaging and the pathway of bacteriophage T4 head assembly.Proceedings of the National Academy of Sciences, 1977
- DNA arrangement in isometric phage headsNature, 1977
- Internal proteins of bacteriophage T7Journal of Molecular Biology, 1976
- Analysis of gene function of bacteriophage phi 29 of Bacillus subtilis: identification of cistrons essential for viral assemblyJournal of Virology, 1976
- Lambda head morphogenesis as seen in the electron microscopeVirology, 1976
- Assembly of the head of bacteriophage P22: X-ray diffraction from heads, proheads and related structuresJournal of Molecular Biology, 1976
- Morphogenesis of bacteriophage Lambda: Electron microscopy of thin sectionsJournal of Molecular Biology, 1976
- Recalibrated linkage map of Escherichia coli K-12.1976
- Buoyant density sedimentation of macromolecules in sodium iothalamate density gradientsJournal of Molecular Biology, 1975