Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of the Platelet Integrin Glycoprotein IIb/IIIa Blocker Integrelin in Elective Coronary Intervention
- 15 April 1995
- journal article
- clinical trial
- Published by Wolters Kluwer Health in Circulation
- Vol. 91 (8), 2151-2157
- https://doi.org/10.1161/01.cir.91.8.2151
Abstract
Background Platelet aggregation and thrombosis have been implicated in the pathogenesis of coronary angioplasty complications. Integrelin, a synthetic cyclic heptapeptide with high affinity and mar...Keywords
This publication has 20 references indexed in Scilit:
- Randomised trial of coronary intervention with antibody against platelet IIb/IIIa iritegrin for reduction of clinical restenosis: results at six monthsThe Lancet, 1994
- Safety and antiplatelet effect of murine monoclonal antibody 7E3 Fab directed against platelet glycoprotein llb/llla in patients undergoing elective coronary angioplastyCoronary Artery Disease, 1993
- Prospects for the use of antagonists to the platelet glycoprotein IIb/ IIIa receptor to prevent postangioplasty restenosis and thrombosisJournal of the American College of Cardiology, 1991
- GPIIb-IIIa: The responsive integrinCell, 1991
- The bleeding time: Its potential utility among patients receiving thrombolytic therapyAmerican Heart Journal, 1990
- Platelets and Thrombolytic TherapyNew England Journal of Medicine, 1990
- Aspirin and Dipyridamole in the Prevention of Re-Stenosis after Percutaneous Transluminal Coronary AngioplastyNew England Journal of Medicine, 1988
- Thrombolysis in myocardial infarction (TIMI) trial—Phase I: Hemorrhagic manifestations and changes in plasma fibrinogen and the fibrinolytic system in patients treated with recombinant tissue plasminogen activator and streptokinaseJournal of the American College of Cardiology, 1988
- Influence of arterial damage and wall shear rate on platelet deposition. Ex vivo study in a swine model.Arteriosclerosis: An Official Journal of the American Heart Association, Inc., 1986
- Molecular Mechanisms of Platelet AggregationAnnual Review of Medicine, 1986