Cupro‐Zinc Superoxide Dismutase:A Possible Biologic Marker for Alcoholism (Studies in Black Patients)
- 1 October 1979
- journal article
- Published by Wiley in Alcohol, Clinical and Experimental Research
- Vol. 3 (4), 291-296
- https://doi.org/10.1111/j.1530-0277.1979.tb05325.x
Abstract
Cupro-zinc superoxide dismutase (SOD-1) was measured by competition radioimmune assay of erythrocyte lysates of alcoholic and control subjects. Normal amounts of SOD-1 were found in the extract from control subjects (815 ng/mg Hb) and from white alcoholics (874 ng/mg Hb). However, the level of SOD-1 in lysates from black alcoholics (1033 ng/mg Hb) was significantly increased (p= 0.0001, rank-sum test) compared with black and white controls. This increase was not related to any other observed hematologic disorder or to any historical, demographic, or laboratory value examined.Keywords
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