N -Ethylmaleimide Inhibition of Horseshoe Crab Hemocyte Agglutination
- 29 May 1964
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 144 (3622), 1147-1148
- https://doi.org/10.1126/science.144.3622.1147
Abstract
The sulfhydryl inhibitor N-ethylmaleimide (NEM) inhibits the agglutination of horseshoe crab hemocytes. The inhibitory action is neutralized by adding cysteine to the NEM before it is mixed with the hemolymph. This new method for arresting horseshoe crab hemocyte agglutination suggests the participation of sulfhydryl groups in the process.Keywords
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