Pharmacological Observations on a Chymotryptic Inhibitor from Potatoes.
- 1 March 1964
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 115 (3), 772-775
- https://doi.org/10.3181/00379727-115-29034
Abstract
An inhibitor of chymotrypsin isolated from potatoes was found to stop the proteolytic activity of the enzyme on fibrin to which the enzyme had already been firmly attached. The inhibitor was nontoxic to mice when injected intravenously or intraperitoneally in amounts as high as 40 mg per kg. It was also nonirritating when applied repeatedly to the conjunctival sac of rabbits' eyes. However, the inhibitor does not change the antigenicity of chymotrypsin.Keywords
This publication has 3 references indexed in Scilit:
- Concerning a Crystalline Chymotryptic Inhibitor from Potatoes, and Its Binding Capacity for the EnzymeJournal of Biological Chemistry, 1963
- AN INHIBITOR OF CHYMOTRYPSIN FROM SOLANUM TUBEROSUM AND ITS BEHAVIOR TOWARD TRYPSINProceedings of the National Academy of Sciences, 1962
- INHIBITION OF THE PROTEINASE AND ESTERASE ACTIVITIES OF TRYPSIN AND CHYMOTRYPSIN BY DIISOPROPYL FLUOROPHOSPHATE: CRYSTALLIZATION OF INHIBITED CHYMOTRYPSINJournal of Biological Chemistry, 1949