Sequential polypeptides. Part VIII. Synthesis of sequential polypeptides containing arginine

Abstract

The suitability of the p-tolysulphonyl group for protecting the guanidino-system in the synthesis of arginine-containing sequential polypeptides by the 2-hydroxyphenyl ester and pentachlorophenyl ester methods has been demonstrated by syntheses of poly-(L-arginyl-L-alanyl-L-alanine) and poly-(L-arginylglycyl-L-proline).