Characterization of anArabidopsis thaliana cDNA homologue to animal poly(ADP‐ribose) polymerase
- 8 May 1995
- journal article
- research article
- Published by Wiley in FEBS Letters
- Vol. 364 (2), 103-108
- https://doi.org/10.1016/0014-5793(95)00335-7
Abstract
A full-lengthArabidopsis thaliana cDNA (app) encoding a protein with high similarity (about 60%) to the catalytic domain of vertebrate poly(ADP-ribose) polymerase (PARP; EC 2.4.2.30) has been cloned. The N-terminal extension of theArabidopsis protein shows similarities with domains of different nuclear and DNA binding proteins in agreement with nuclear localization and putative function of a plant PARP. APP is encoded by a single gene mapped at the top of chromosome 4 of theArabidopsis genome and mRNA is abundant in cell suspension culture compared to its accumulation in whole plant.Keywords
This publication has 30 references indexed in Scilit:
- Regulation by ADP-ribosylationTrends in Cell Biology, 1995
- Induction of intrachromosomal homologous recombination in whole plantsThe Plant Journal, 1995
- Nicotinamide, a missing link in the early stress response in eukaryotic cells: A hypothesis with special reference to oxidative stress in plantsFEBS Letters, 1994
- A molecular evolutionary framework for eukaryotic model organismsCurrent Biology, 1994
- Dual Function for Poly(ADP-ribose) Synthesis in Response to DNA Strand BreakageBiochemistry, 1994
- cDNA cloning and expression of an Arabidopsis GTP‐binding protein of the ARF familyFEBS Letters, 1993
- Enzymological properties of poly(ADP-ribose)polymerase: characterization of automodification sites and NADase activityBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1991
- PHYLOGENIES FROM MOLECULAR SEQUENCES: INFERENCE AND RELIABILITYAnnual Review of Genetics, 1988
- Poly(A) polymerase and poly(ADP‐ribose) polymerase activities in normal and crown gall tumor tissue cultures of tobaccoFEBS Letters, 1985
- Effect of polyamines and Mg++ on poly(ADP-ribose) synthesis and ADP-ribosylation of histones in wheatBiochemical and Biophysical Research Communications, 1979