Soluble cerebral proteins in normal and oedematous brain

Abstract

The soluble cerebral proteins of cortex and white matter from normal brains of adults and infants and of oedematous brain tissue have been subjected to starch electrophoresis. The protein patterns with their nitrogen, lactic dehydrogenase, and glutamic oxalacetic transaminase contents were estimated. The normal patterns of these substances have been compared with the findings of workers using other methods of electrophoresis. Oedematous brains have been shown to possess an albumin band with an increase in lactic dehydrogenase in some globulin bands. These findings are discussed in relation to the mode and site of production of oedema.