The Duhring chamber

Abstract

For assessing [human] skin reactions to irritants and allergens, chambers which confine the test substance to the site of application are much superior to conventional patch tests. Because the concentration and volume do not change appreciably, the method allows for quantification and yields more reproducible results. A new aluminum chamber was designed which is more useful than its predecessor, the Finn chamber, mainly because of its increased capacity. The intensity of irritant and allergic reactions is dependent on the quantities applied.