CALCIUM AS A GOITROGEN*
- 1 November 1954
- journal article
- research article
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 14 (11), 1412-1422
- https://doi.org/10.1210/jcem-14-11-1412
Abstract
Rats on a low-I diet showed thyroid hyperplasia and increased radio-I uptake. Addition of 2% CaCo3 to diet increased these changes. Absorption of iodide from the gut was not inhibited by CaCo3. Iodide trapping mechanism of thyroid was not diminished. The mechanism of action of CaCo3 appeared to be either inhibition of thyroxine synthesis or increased iodide clearance by kidney.Keywords
This publication has 2 references indexed in Scilit:
- Goitrogenic Action of Calcium and Vitamin DJournal of Nutrition, 1943
- Studies on the Relation of Diet to GoiterJournal of Nutrition, 1933