Significance of alpha-subunit HCG demonstrated in breast carcinomas by the immunoperoxidase technique.
Open Access
- 1 March 1978
- journal article
- research article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 31 (3), 245-249
- https://doi.org/10.1136/jcp.31.3.245
Abstract
Fifty-three breast carcinomas were examined by an indirect immunoperoxidase technique for the presence of the alpha-subunit of human chorionic gonadotrophin. Positive staining occurred in 12 (22.6%). There was no correlation between alpha-subunit production and specific histological features, but production was related to the presence of lymph node metastases and hence a poorer prognosis. The alpha-subunit could be used as a prognostic indicator in the assessment of breast carcinoma.Keywords
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