Age-Dependent Increase ofCampylobacter pyloriAntibodies in Blood Donors
- 1 January 1989
- journal article
- research article
- Published by Taylor & Francis in Scandinavian Journal of Gastroenterology
- Vol. 24 (1), 110-114
- https://doi.org/10.3109/00365528909092247
Abstract
Antibodies against Campylobacter pylori were determined in 500 blood donors aged 18 to 65 years. Acid extract from a C. pylori strain was used as antigen in enzyme irnmunoassay. the proportion of donors with high antibody titers increased with age. for IgG antibodies it was 10% in the age group from 18 to 25 years but 60% in the group from 56 to 65 years; the increase for IgA and IgM antibodies was from 5 to 42% and from 7 to 21%, respectively. the geometric mean titers of those with high values showed no clear changes with age, which would imply chronic antigenic stimulus.Keywords
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