Double identity for proteins of the Bcl-2 family
- 19 June 1997
- journal article
- review article
- Published by Springer Nature in Nature
- Vol. 387 (6635), 773-776
- https://doi.org/10.1038/42867
Abstract
Bcl-2 is an oncogenic protein that acts by inhibiting programmed cell death. The mechanisms used by this and related anti-apoptotic proteins to protect cells from cytotoxic stimuli are now emerging, with the discovery that Bcl-2 can function both as an ion channel and as an adaptor or docking protein.Keywords
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