Phosphonoacetic Acid in the Treatment of Experimental Herpes Simplex Keratitis
- 1 March 1975
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 7 (3), 285-288
- https://doi.org/10.1128/aac.7.3.285
Abstract
In a rabbit model of herpes simplex corneal ulceration, 5% phosphonoacetic acid solution or ophthalmic ointment suppressed clinical disease and virus replication. The effect of 5% phosphonoacetic acid ointment was equivalent to that of 0.5% idoxuridine ointment in the treatment of this established herpetic eye infection.Keywords
This publication has 7 references indexed in Scilit:
- Proflavine and Light in the Treatment of Experimental Herpetic Ocular InfectionsAntimicrobial Agents and Chemotherapy, 1974
- Suppression of herpes simplex virus infection by phosphonoacetic acid.1973
- Enhancement of Virus Multiplication and Interferon Production by Cortisone in Ocular Herpesvirus InfectionThe Journal of Immunology, 1970
- Structural Changes in Chronic Herpetic KeratitisArchives of Ophthalmology (1950), 1968
- PECULIARITIES OF ANTIVIRAL ACTION OF DIBENZYLPHOSPHINIC ACID1967
- Antiviral Activity of p-Nitrobenzylphosphonic AcidNature, 1965
- SUPERFICIAL HERPETIC KERATITIS TREATED WITH 5-IODO-2'-DEOXYURIDINEBritish Journal of Ophthalmology, 1964