Excitatory and Inhibitory Effects of Serotonin on Sensorimotor Reactivity Measured with Acoustic Startle
- 25 July 1980
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 209 (4455), 521-523
- https://doi.org/10.1126/science.7394520
Abstract
Serotonin infused into the lateral ventricle in rats produced a dose-dependent depression of the acoustic startle reflex. When infused onto the spinal cord, serotonin produced a dose-dependent increase in startle. Thus the same neurotransmitter can modulate the same behavior in opposite ways, depending on which part of the central nervous system is involved.Keywords
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