The myenteric plexus in drug-induced neuropathy.
- 1 December 1967
- journal article
- research article
- Published by BMJ in Journal of Neurology, Neurosurgery & Psychiatry
- Vol. 30 (6), 506-510
- https://doi.org/10.1136/jnnp.30.6.506
Abstract
Functional abnormalities of the large intestine were produced by intraperitoneal administration of vinblastine sulfate, mepacrine methanesulfate and isonicotinic acid hydrazide in mice. Microscopic damage to the myenteric plexus was evident. Drug-induced damage to the myenteric plexus in the large intestine provides a means of assessing neurotoxicity in known and unknown substances.This publication has 5 references indexed in Scilit:
- On the pattern of change in peripheral nerves produced by isoniazid intoxication in ratsJournal of Neurology, Neurosurgery & Psychiatry, 1967
- Spheromembranous Degeneration of Muscle Induced by VincristineArchives of Neurology, 1966
- ENTEROMEGALY AND STEATORRHEA IN RAT FOLLOWING INTRAPERITONEAL QUINACRINE (ATABRINE)1966
- Vinblastine Sulphate in the Treatment of Malignant DiseaseBritish Journal of Cancer, 1965
- EXPERIMENTAL STUDIES ON THE INNERVATION OF THE MUCOUS MEMBRANE OF THE GUTBrain, 1960