Experimental Observations on Short and Long-Term Effects of Arterial Occlusion with Ivalon

Abstract

Ivalon sponge in dogs is a useful embolic material, particularly when long-term or permanent occlusions are desirable. Ivalon is well tolerated and produces little if any damage to the wall or periadventitial tissues of the embolized artery. Definite evidence of inflammatory reaction in the wall of the embolized arteries was seen; these changes were seen only in the acute phase and seem to be secondary to damage of the vessel wall by the plastic material. Permanent occlusion results with disappearance of the inflammatory changes at 9 mo. post-embolization.