Human Heart and Platelet Actins Are Products of Different Genes
- 9 January 1976
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 191 (4222), 94-95
- https://doi.org/10.1126/science.1246600
Abstract
The amino acid sequences of selected cyanogen bromide peptides from human blood platelet actin and human cardiac muscle actin were compared; it was found that, at position 129, platelet actin has threonine, and that cardiac muscle actin has valine. Thus human cytoplasmic and myofibrillar actins must be synthesized under the control of different genes.Keywords
This publication has 15 references indexed in Scilit:
- Non-identity of muscle and non-muscle actinsBiochemical and Biophysical Research Communications, 1975
- Identification of actin in situ at the ectoplasm-endoplasm interface of Nitella. Microfilament-chloroplast association.The Journal of cell biology, 1975
- A second form of actin: Platelet microfilaments depolymerized by ATP and divalent cationsArchives of Biochemistry and Biophysics, 1975
- Solid‐phase edman degradation: Attachment of carboxyl‐terminal homoserine peptides to an insoluble resinFEBS Letters, 1973
- The Characterization of Contractile Proteins from Platelets and FibroblastsCold Spring Harbor Symposia on Quantitative Biology, 1973
- Cytoplasmic Actin: A Comparative StudyCold Spring Harbor Symposia on Quantitative Biology, 1973
- The amino acid sequence around four cysteine residues in trout actinBiochemical Journal, 1971
- Amino acid sequence studies on rabbit skeletal muscle actin. Cyanogen bromide cleavage of the protein and determination of the sequences of seven of the resulting peptidesBiochemistry, 1970
- FORMATION OF ARROWHEAD COMPLEXES WITH HEAVY MEROMYOSIN IN A VARIETY OF CELL TYPESThe Journal of cell biology, 1969
- Electron microscope studies on the structure of natural and synthetic protein filaments from striated muscleJournal of Molecular Biology, 1963