Cardiac Atria of BIO 14.6 Hamsters Are Deficient in Natriuretic Factor
- 24 February 1984
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 223 (4638), 820-822
- https://doi.org/10.1126/science.6538050
Abstract
The hearts of 220-day-old hamsters of the BIO 14.6 strain are deficient in atrial natriuretic factor; saline extracts of atria produce one-third the natriuretic and diuretic effects of extracts of atria from age-matched normal hamsters. BIO 14.6 hamsters are known to develop congestive heart failure with edema when they are about 200 days old, and the venous congestion and edema are preventable by parabiosis with normal hamsters. The humoral mediator, the deficiency of which causes venous congestion and edema in BIO 14.6 hamsters, may be atrial natriuretic factor.This publication has 22 references indexed in Scilit:
- Purification and Sequence Analysis of Bioactive Atrial Peptides (Atriopeptins)Science, 1984
- Bioactive Cardiac Substances: Potent Vasorelaxant Activity in Mammalian AtriaScience, 1983
- A rapid and potent natriuretic response to intravenous injection of atrial myocardial extract in ratsLife Sciences, 1981
- Role of cardiac, pulmonary, and carotid mechanoreceptors in the control of hind-limb and renal circulation in dogs.Circulation Research, 1975
- Natriuretic HormoneNephron, 1975
- Natriuretic activity in plasma and urine of salt-loaded man and sheepJournal of Clinical Investigation, 1969
- SPONTANEOUS, HEREDITARY MYOCARDIAL DEGENERATION AND CONGESTIVE HEART FAILURE IN A STRAIN OF SYRIAN HAMSTERS*Annals of the New York Academy of Sciences, 1969
- SPECIFIC GRANULES IN ATRIAL MUSCLE CELLSThe Journal of cell biology, 1964
- EVIDENCE FOR SECRETION OF AN ALDOSTERONE-STIMULATING HORMONE BY THE KIDNEY*Journal of Clinical Investigation, 1961
- Response of Normal Subjects to Large Amounts of Aldosterone1Journal of Clinical Investigation, 1958