Self-administered Topical 5% Imiquimod Cream for External Anogenital Warts

Abstract

ALTHOUGH GENITAL warts are common, therapy is generally painful, prolonged, variably effective, and characterized by recurrence. One reason for these therapeutic problems is that most current therapies depend on physical destruction of the tumor rather than direct antiviral activity against the causative agent, human papillomavirus. A treatment for anogenital warts that is specifically antiviral and nondestructive would represent a significant advancement.